Vesicular Carriers for Phytochemical Delivery: A Comprehensive Review of Techniques and Applications

Vesicular Carriers for Phytochemical Delivery: A Comprehensive Review of Techniques and Applications

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Natural substances, especially those derived from plants, exhibit a diverse range of therapeutic benefits, such as antioxidant, anti-inflammatory, anticancer, and antimicrobial effects.Nevertheless, their use in clinical settings is frequently impeded by inadequate solubility, limited bioavailability, and instability.Nanovesicular carriers, such as liposomes, niosomes, ethosomes, transferosomes, transethosomes, and cubosomes, have emerged as innovative phytochemical delivery systems to address these limitations.This review highlights recent developments in vesicular nanocarriers for phytochemical delivery, here emphasizing preparation techniques, composition, therapeutic applications, and the future potential of these systems.Phytosomes, along with old taylor whiskey 1933 price their key advantages and various preparation techniques, are extensively described.

Various in vitro and in vivo characterization techniques utilized for evaluating these nanovesicular carriers are summarized.Completed clinical trials and patents granted for nanovesicles encapsulating phytochemicals designed for systemic delivery are tabulated.Phytochemical delivery via vesicular carriers faces challenges such as low stability, limited active loading, scalability issues, and high production costs.Additionally, immune clearance and regulatory hurdles hinder clinical application, requiring improved copyright design and formulation techniques.